FRUK-tohs
Macronutrient
The natural sugar found in fruits — healthy in whole fruit form but potentially harmful in large amounts from processed foods because your liver handles all of it directly.
| Group | Recommended | Source |
|---|---|---|
| Adult male | No RDA; limit added fructose to <25g/day (AHA). Fruit fructose typically 15-20g/day is safe | AHA/WHO |
| Adult female | No RDA; limit added fructose to <25g/day | AHA/WHO |
| Pregnancy | Limit added fructose; moderate fruit intake encouraged | WHO |
| Children | Limit added sugars to <25g/day total | AHA |
| Older adults | Same as adults; monitor for metabolic syndrome risk | AHA |
| Food | Amount | Where |
|---|---|---|
| Honey | 40g fructose per 100g | global |
| Agave nectar | 56g fructose per 100g | mesoamerica |
| Apple | 6g fructose per 100g | global |
| Mango | 4.7g fructose per 100g | south-asia |
| Dates (dried) | 32g fructose per 100g | middle-east |
| Grapes | 8.1g fructose per 100g | global |
| Jackfruit | 9.5g fructose per 100g | southeast-asia |
| Watermelon | 3.4g fructose per 100g | global |
Mild: No clinical deficiency — fructose is not essential
Moderate: Not applicable — glucose can fulfill all energy needs
Severe: Not applicable
Time to onset: Not applicable — fructose deficiency does not occur
Upper limit: WHO recommends <10% of calories from free sugars (~50g/day total added sugars). Fructose-specific concern begins >50g/day from added sources
NAFLD, elevated triglycerides, insulin resistance, hyperuricemia and gout, visceral fat accumulation, metabolic syndrome
Absorbed via GLUT5 transporter in small intestine; capacity ~25-50g per sitting (varies individually). Excess causes malabsorption, bloating, diarrhea
Helped by: Glucose co-ingestion (improves fructose absorption via GLUT2 activation), Gradual intake (allows transporter upregulation)
Hindered by: Fructose malabsorption (affects ~30-40% of people at doses >25g), Sorbitol (competes for GLUT5)
Heat-stable at cooking temperatures. Caramelizes at lower temperature than glucose, creating browning and flavor. High-fructose corn syrup in processed foods is the primary concern, not naturally occurring fructose in cooked whole foods.
Evidence grades: A — meta-analyses / large trials; B — cohort studies & guidelines; C — expert consensus. Links open in a new tab.