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Manganese

MANG-guh-neez

Mineral

A trace mineral that protects your cells from damage, helps form strong bones and cartilage, and aids blood sugar regulation.

Manganese in your mitochondria works like a personal bodyguard — its enzyme MnSOD neutralizes the dangerous free radicals produced during energy generation, protecting the cell's power plants.

What it does in the body

  • Antioxidant defense (MnSOD in mitochondria)
  • Bone and cartilage formation (glycosyltransferases)
  • Gluconeogenesis and carbohydrate metabolism
  • Wound healing (proline synthesis for collagen)
  • Urea cycle function (arginase)

How much you need (Daily Value)

GroupRecommendedSource
Adult male2.3 mg (AI)NIH/IOM
Adult female1.8 mg (AI)NIH/IOM
Pregnancy2.0 mg (AI)IOM
Children1.2 mg (1-3y), 1.5 mg (4-8y), 1.6-2.2 mg (9-18y)NIH/IOM
Older adults2.3 mg (men), 1.8 mg (women)NIH/IOM

Richest food sources

FoodAmountWhere
Mussels6.8 mg per 100gcoastal regions
Hazelnuts6.2 mg per 100gEurope/Turkey
Brown rice (cooked)1.1 mg per 100gEast/South Asia
Oatmeal (cooked)1.4 mg per 100gglobal
Pineapple0.9 mg per 100gTropics
Spinach (cooked)0.9 mg per 100gglobal
Black tea (brewed)0.5 mg per 100mlglobal
Chickpeas (cooked)1.0 mg per 100gMiddle East/South Asia

If you don't get enough

Mild: Impaired growth, altered carbohydrate metabolism

Moderate: Skeletal abnormalities, impaired glucose tolerance, altered lipid metabolism

Severe: Extremely rare in humans — experimental deficiency causes dermatitis, impaired bone growth, reproductive abnormalities

Time to onset: Deficiency is exceedingly rare in humans due to widespread presence in food.

Too much

Upper limit: 11 mg/day (adults)

Manganism: Parkinson-like syndrome with psychiatric symptoms ('manganese madness'), tremor, gait disturbance. Primarily from inhalation exposure or contaminated water. Liver disease impairs biliary excretion, increasing risk.

How well you absorb it

1-5% from diet (very low; tightly regulated)

Helped by: Low iron status (upregulates shared transporter DMT-1), Ascorbic acid, Histidine

Hindered by: Iron (competes for DMT-1), Calcium, Phytate, Oxalate, Tea (tannins)

Cooking & storage

Manganese is heat-stable. Milling and refining grains removes significant manganese — whole grains contain up to 10x more manganese than refined grains. Tea brewing extracts substantial manganese.

Did you know. Dietary manganese deficiency is virtually unknown in free-living populations. The greater public health concern is manganese toxicity from contaminated groundwater, affecting millions in South Asia, particularly Bangladesh.

Educational reference only. Nutrient needs vary with age, sex, health, and medication. Not medical or dietary advice. See our full disclaimer.
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Evidence grades: A — meta-analyses / large trials; B — cohort studies & guidelines; C — expert consensus. Links open in a new tab.

AManganese Fact Sheet for Health Professionals — NIH Office of Dietary Supplements, 2024
AManganese in Drinking Water — WHO, 2021