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Vitamin C (Ascorbic Acid)

VIT-uh-min SEE / as-KOR-bik AS-id

Vitamin

The immune-boosting, collagen-building vitamin found in fruits and vegetables that humans uniquely cannot make on their own.

Vitamin C is like the mortar between bricks — it's essential for making collagen, which holds your body's tissues together. Without mortar, the brick wall crumbles, just like tissues do in scurvy.

What it does in the body

  • Collagen synthesis (essential cofactor for prolyl and lysyl hydroxylases)
  • Antioxidant defense (primary aqueous-phase free radical scavenger)
  • Non-heme iron absorption enhancement (reduces Fe3+ to Fe2+ in the gut)
  • Carnitine synthesis (required for fatty acid transport into mitochondria)
  • Neurotransmitter synthesis (dopamine beta-hydroxylase cofactor for norepinephrine)

How much you need (Daily Value)

GroupRecommendedSource
Adult male90 mgNIH/IOM
Adult female75 mgNIH/IOM
Pregnancy85 mgWHO/IOM
Children15-45 mg (ages 1-13)WHO
Older adults90 mg (male), 75 mg (female); smokers add 35 mg/dayNIH

Richest food sources

FoodAmountWhere
Kakadu plum (Terminalia ferdinandiana)2300-3150 mg per 100gAustralia (Aboriginal)
Camu camu2400 mg per 100gSouth America (Amazon)
Guava228 mg per 100gTropics/Central America
Red bell pepper128 mg per 100gglobal
Kiwifruit93 mg per 100gNew Zealand/global
Orange53 mg per 100gglobal
Broccoli (cooked)65 mg per 100gglobal
Indian gooseberry (Amla)600 mg per 100gSouth Asia

If you don't get enough

Mild: Fatigue, irritability, poor wound healing, easy bruising

Moderate: Perifollicular hemorrhage, corkscrew hairs, gingival inflammation and bleeding, arthralgia

Severe: Scurvy: spontaneous hemorrhage, tooth loss, anemia, bone pain, impaired wound healing, death if untreated

Time to onset: Plasma levels decline within 1-3 weeks without intake; clinical scurvy in 1-3 months of total vitamin C deprivation

Too much

Upper limit: 2000 mg/day for adults

GI distress (nausea, diarrhea, cramping) at >2g/day. Increased oxalate production with risk of kidney stones in susceptible individuals. False negative fecal occult blood test. In G6PD deficiency, high IV doses can cause hemolysis.

How well you absorb it

~70-90% at moderate intakes (30-180 mg); decreases to ~50% at 1000 mg; <16% at 12,000 mg due to saturated SVCT1 transport

Helped by: Consuming with food, Organic acids in fruits, Divided doses throughout the day

Hindered by: Smoking (increases turnover by 40%), Aspirin (competes for absorption), Heat and oxidation during cooking, Alkaline cooking conditions

Cooking &amp; storage

Vitamin C is the most heat-sensitive and water-soluble vitamin. Boiling destroys 50-75% of vitamin C. Steaming retains 80-90%. Cutting and exposing to air oxidizes vitamin C. Cooking in copper pots accelerates destruction. Best consumed raw when possible.

Did you know. Scurvy is not just historical — recent studies found subclinical deficiency (plasma <11 mcmol/L) in 5-17% of US adults and higher in low-income populations. Globally, vitamin C deficiency is estimated to affect up to 7.1% of the population.

Educational reference only. Nutrient needs vary with age, sex, health, and medication. Not medical or dietary advice. See our full disclaimer.
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Evidence grades: A — meta-analyses / large trials; B — cohort studies & guidelines; C — expert consensus. Links open in a new tab.

AVitamin C Fact Sheet for Health Professionals — NIH Office of Dietary Supplements, 2023
AVitamin C and Immune Function — Nutrients, 2017
BPrevalence of vitamin C deficiency in the United States — American Journal of Clinical Nutrition, 2009