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Vitamin E (Tocopherol)

VIT-uh-min EE / toh-KOF-er-all

Vitamin

A powerful antioxidant that protects your cell membranes from damage, like a bodyguard for your cells.

Vitamin E is like a sacrificial shield — it takes the hit from free radicals so your cell membranes don't have to, then gets recycled by vitamin C for another round.

What it does in the body

  • Lipid peroxidation chain-breaking antioxidant in cell membranes
  • Immune cell function enhancement (T-cell proliferation)
  • Anti-platelet aggregation and vasodilation
  • Protection of LDL from oxidation
  • Neurological function maintenance

How much you need (Daily Value)

GroupRecommendedSource
Adult male15 mg alpha-tocopherolNIH/IOM
Adult female15 mg alpha-tocopherolNIH/IOM
Pregnancy15 mg alpha-tocopherolWHO/IOM
Children6-11 mg (ages 1-13)WHO
Older adults15 mg alpha-tocopherolNIH

Richest food sources

FoodAmountWhere
Wheat germ oil20.3 mg per tablespoonglobal
Sunflower seeds35.2 mg per 100gglobal
Almonds25.6 mg per 100gMediterranean/Americas
Hazelnuts15.0 mg per 100gEurope/Turkey
Avocado2.1 mg per 100gAmericas
Red palm oil15.9 mg tocotrienols per 100mlWest Africa/Southeast Asia
Spinach (cooked)2.1 mg per 100gglobal
Olive oil (extra virgin)14.4 mg per 100mlMediterranean

If you don't get enough

Mild: Increased oxidative stress markers, mildly impaired immune response

Moderate: Peripheral neuropathy, myopathy, retinopathy

Severe: Spinocerebellar ataxia (ataxia with vitamin E deficiency — AVED), hemolytic anemia in premature infants, severe neuropathy

Time to onset: 5-10 years to deplete body stores in adults; premature infants can become deficient within weeks

Too much

Upper limit: 1000 mg (1500 IU natural, 1100 IU synthetic)/day for adults

Increased bleeding risk (inhibits vitamin K-dependent clotting factors), nausea, diarrhea, fatigue. Meta-analyses suggest increased all-cause mortality at >400 IU/day.

How well you absorb it

20-80% depending on fat content of meal; absorbed via micelle formation in small intestine

Helped by: Dietary fat (medium and long-chain), Concurrent vitamin C (regenerates oxidized vitamin E), Selenium (works synergistically in glutathione peroxidase system)

Hindered by: Very low-fat diets, Mineral oil, Olestra, Iron supplements (can oxidize vitamin E in the gut)

Cooking & storage

Vitamin E is moderately heat-sensitive. Frying at high temperatures destroys 30-50% of vitamin E. Refining of vegetable oils removes significant amounts. Cold-pressed oils retain more vitamin E.

Did you know. Up to 90% of Americans do not meet the estimated average requirement for vitamin E from food alone, though clinical deficiency is rare due to adipose tissue stores.

Educational reference only. Nutrient needs vary with age, sex, health, and medication. Not medical or dietary advice. See our full disclaimer.
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Evidence grades: A — meta-analyses / large trials; B — cohort studies & guidelines; C — expert consensus. Links open in a new tab.

AVitamin E Fact Sheet for Health Professionals — NIH Office of Dietary Supplements, 2023
AMeta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality — Annals of Internal Medicine, 2005
BVitamin E: Function and Metabolism — Free Radical Biology and Medicine, 2019