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Vitamin K (Phylloquinone/Menaquinone)

VIT-uh-min KAY / fil-oh-KWIN-ohn / men-ah-KWIN-ohn

Vitamin

The 'clotting vitamin' that stops bleeding and also helps keep calcium in your bones instead of your arteries.

Vitamin K is like the clotting switch that turns on your body's bandage-making factory. Without it, even a small cut could bleed for a dangerously long time.

What it does in the body

  • Activation of coagulation factors (II, VII, IX, X) and anticoagulant proteins (C, S, Z)
  • Osteocalcin carboxylation for bone mineralization
  • Matrix GLA protein activation preventing arterial calcification
  • Cell growth regulation and apoptosis
  • Anti-inflammatory effects via suppression of NF-kB signaling

How much you need (Daily Value)

GroupRecommendedSource
Adult male120 mcgNIH/IOM
Adult female90 mcgNIH/IOM
Pregnancy90 mcgWHO/IOM
Children30-75 mcg (ages 1-13)WHO
Older adults120 mcg (male), 90 mcg (female)NIH

Richest food sources

FoodAmountWhere
Natto (fermented soybeans)1103 mcg MK-7 per 100gJapan
Kale (raw)817 mcg K1 per 100gglobal
Collard greens (cooked)623 mcg K1 per 100gAmericas/Africa
Spinach (cooked)493 mcg K1 per 100gglobal
Broccoli (cooked)141 mcg K1 per 100gglobal
Gouda cheese73 mcg MK per 100gEurope
Chicken liver13 mcg MK-4 per 100gglobal
Sauerkraut4.8 mcg K2 per 100gCentral/Eastern Europe

If you don't get enough

Mild: Elevated undercarboxylated osteocalcin, subtle coagulation changes (prolonged PT)

Moderate: Easy bruising, prolonged bleeding from wounds, epistaxis

Severe: Hemorrhagic disease (particularly neonates), uncontrolled bleeding, intracranial hemorrhage in infants

Time to onset: 1-2 weeks without dietary intake (body stores are limited compared to other fat-soluble vitamins)

Too much

Upper limit: No established UL for K1 or K2; considered safe even at high doses

Natural K1/K2 have no known toxicity. Synthetic menadione (K3) can cause hemolytic anemia and jaundice, especially in infants — no longer used clinically.

How well you absorb it

K1 from vegetables: 5-15%; K1 from oils/supplements: 80%; K2 (MK-7): nearly 100%

Helped by: Dietary fat, Processing/cooking of vegetables (releases K1 from chloroplast membranes), Bile salts

Hindered by: Fat malabsorption, Broad-spectrum antibiotics (kill K2-producing gut bacteria), Warfarin (antagonist), High-dose vitamin A or E

Cooking & storage

Vitamin K1 is heat-stable and not significantly destroyed by cooking. Cooking with oil actually enhances K1 absorption from leafy greens by increasing fat availability.

Did you know. Subclinical vitamin K deficiency (elevated undercarboxylated osteocalcin) is estimated to affect up to 30% of the general population and may contribute to osteoporosis and cardiovascular calcification.

Educational reference only. Nutrient needs vary with age, sex, health, and medication. Not medical or dietary advice. See our full disclaimer.
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Evidence grades: A — meta-analyses / large trials; B — cohort studies & guidelines; C — expert consensus. Links open in a new tab.

AVitamin K Fact Sheet for Health Professionals — NIH Office of Dietary Supplements, 2023
AVitamin K-dependent carboxylation of coagulation factors — Thrombosis and Haemostasis, 2020
BVitamin K2 supplementation and bone health — Osteoporosis International, 2021